Epigenome Lab
PRINCESS MARGARET CANCER CENTRE - TORONTO
Elias Orouji, MD, PhD
Epigenome Lab at Princess Margaret Genomics Centre
Epigenome Lab at Princess Margaret Genomics Centre
Our research is focused on the epigenomic characterization of human cells in the process of evolving into pre-cancerous and eventually tumor lesions. We are particularly interested in the exploring chromatin state transitions using various computational approaches in cancer progression. Our findings can be leveraged to develop therapeutic compounds that will specifically target such alterations in chromatin states.
Epigenomics | Chromatin states | 3D genome architecture | Cancer epigenetics | Targeted therapies
Chromatic State Dynamics in CRC
CRC Epigenomic Subtypes
'EpiC' Therapeutic Approach